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revlimid information in heavily pretreated sufferers, different alternatives for first-line therapy, and the potential for life-threatening tumor flare and different toxicities related to lenalidomide, this agent should solely be thought of as a part of a properly-designed clinical trial despite its FDA approval for other indications (MDS and multiple myeloma).
revlimid online pharma follows publication of the ultimate data from the phase III FIRST trial , which demonstrated a big enchancment within the median Progression-Free Survival (PFS) in transplant-ineligible Newly Diagnosed (ND) MM sufferers given steady lenalidomide plus dexamethasone (Rd continuous), in comparison with melphalan, prednisone, and thalidomide (MPT).
In medical trials, 15% of patients skilled hepatotoxicity (with hepatocellular, cholestatic and combined characteristics); 2% of patients with MM and 1% of patients with myelodysplasia had critical hepatotoxicity occasions. If you're about to be began on any new medicine, remind your doctor, dentist or pharmacist that you're taking Revlimid.
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The approval of ixazomib, a proteasome inhibitor , was based on the results of a big randomized scientific trial of 722 patients by which sufferers handled with ixazomib together with lenalidomide and dexamethasone had longer median progression-free survival than those who received lenalidomide and dexamethasone alone: 20.6 months versus 14.7 months.
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